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You are here: Home / Events / PREMIO GIOVANI BIOLOGI 2017 - PLENARY LECTURE - Prof. Alfonso Martinez-Arias: “Genetically supervised self-organization of mouse ES cells: the embryo redux”

PREMIO GIOVANI BIOLOGI 2017 - PLENARY LECTURE - Prof. Alfonso Martinez-Arias: “Genetically supervised self-organization of mouse ES cells: the embryo redux”

PREMIO GIOVANI BIOLOGI - Plenary Lecture - Department of Genetics - University of Cambridge - Cambridge, United Kingdom Email: a.martinezarias@gen.cam.ac.uk Websites: http://www.gen.cam.ac.uk/research-groups/martinez-arias http://amapress.gen.cam.ac.uk/
When Sep 25, 2017
from 11:00 AM to 12:00 PM
Where CNR Conference Room
Contact Name
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Alfonso Martinez Arias (AMA; PI) is Professor of Developmental Mechanics in the Department of Genetics, University of Cambridge, with interest and expertise on the role that interactions between signaling and transcription factor networks play in cell fate decisions. He has a long term interest and expertise in how signalling and transcriptional networks interact during cell fate decisions. For the last eight years he has been pursuing this in the context of a Systems Biology approach using mouse Embryonic Stem Cells (mESCs) and has pioneered the use of these cells as a model for developmental systems biology. Of particular relevance to this application is his finding that under controlled cultured conditions, small aggregates of mESCs undergo symmetry breaking, germ layer specification and axial organization in a manner that mimics events in embryos. This finding has opened up the possibility to bypass the use of animals in the study of early mammalian development and has paved the way for the studies proposed here. AMA is an elected member of EMBO, has been a holder of a Wellcome Senior Fellowship and the recipient of multiple grants from the BBSRC and The Wellcome Trust, he has also held an HFSP and an ERC Advanced Investigator grant. He has not held support from the MRC since his appointment to the MRC LMB staff (1986-87). In 2012 he was awarded the Waddington Medal of the BSDB in recognition of his sustained and significant and contributions to developmental biology. He has been driver of quantitative approaches to developmental biology in the UK and is the initiator and organizer of meetings on this subject, most notably The Physics of Living Matter, now on its 12th year and recently in bridging the gap between developmental biologists and engineers. He is also actively involved in promoting changes in biomedical publishing.

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