{"id":10286,"date":"2021-10-27T11:38:58","date_gmt":"2021-10-27T09:38:58","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=10286"},"modified":"2025-10-22T09:20:37","modified_gmt":"2025-10-22T07:20:37","slug":"gemma-flore","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/gemma-flore\/","title":{"rendered":"Gemma Flore"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\"DSC_0281\"\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t
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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Gemma Flore<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Researcher<\/span><\/strong><\/h3>

\"\" +39 081 6132226 \u00a0 \"\" gemma.flore@igb.cnr.it<\/strong><\/p>

Embryonic Development and Biology of Stem Cells<\/span><\/strong><\/span><\/p>

Keywords: : <\/strong>neurodevelopmental disorders, genetic rare diseases, mouse models, preclinical drug trials,\u00a0 22q11.2DS, TBX1<\/p>

\u00a0<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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  • \n \n \n \n Research Interest<\/span> <\/li>\n
  • \n \n \n \n Selected Publications<\/span> <\/li>\n
  • \n \n \n \n Professional Experience<\/span> <\/li>\n <\/ul>\n <\/div>\n \n
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    My general research interest is in investigating neurodevelopmental disorders in rare diseases, through genetically engineered mouse models.<\/p>

    In the last years \u00a0I\u2019ve been focused on understanding the molecular basis of psychiatric and behavioral disorders reported\u00a0 in DiGeorge Syndrome (22q11.2DS). In the lab, we individuated \u00a0brain developmental abnormalities probably underlying the neurological symptoms and \u00a0evaluated \u00a0innovative pharmacological strategies to rescue them.<\/p>

    These studies are now pointing to preclinical and clinical trials aiming to improve the psychiatric\u00a0 and behavioral clinical signs, which have the major impact on the quality of life of the patients and their families.<\/p>

    In the past years my research activity was also involved in description of more general mechanisms of brain development, by getting inside the role of the transcription factor COUP-TF I . In the working group we addressed specific function of this brain master gene during neocortical and archicortical development as in adult neurogenesis, and we had the opportunity to find new correlations about hippocampal regions and \u00a0the \u201cGPS\u201d function of the brain.<\/p> <\/div>\n\t\t \n

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    Caterino M*, Paris D*, Torromino G*, Costanzo M, Flore G<\/strong>, Tramice A, Golini E, Mandillo S, Cavezza D, Angelini C, Ruoppolo M, Motta A, De Leonibus E, Baldini A, Illingworth E, Lania G. Brain and behavioural anomalies caused by Tbx1 haploinsufficiency are corrected by vitamin B12. Life Sci Alliance. 2024 Nov 20;8(2):e202403075. doi: 10.26508\/lsa.202403075. PMID: 39567195; PMCID: PMC11579592.

    Deloulme JC*, Leclercq M*, Deschaux O, Flore G<\/strong>, Capellano L, Tocco C, Braz BY, Studer M, Lahrech H. Structural interhemispheric connectivity defects in mouse models of BBSOAS: Insights from high spatial resolution 3D white matter tractography. Neurobiol Dis. 2024 Apr;193:106455. doi: 10.1016\/j.nbd.2024.106455. Epub 2024 Feb 24. PMID: 38408685.<\/p>

    Favicchia I* and Flore G*,<\/strong>Cioffi S, Lania G.,Baldin A.,Illingworth E.( *Equal Contributors) Pharmacological rescue of the brain cortex phenotype of Tbx1 mouse mutants: significance for 22q11.2 deletion syndrome .Front Mol Neurosci.2021 Sep 6; 14:663598. doi:10.3389\/fnmol.2021.663598. eCollection 2021 ISSN :1662-5099; WOS:000764234600001; Scopus: 2-s2.0-85115130273<\/p>

    Cioffi S., Turturo MG., Martucciello S., Flore G<\/strong>., Baldini A.,\u00a0\u00a0 Illingworth E. (2019)Defining Vegfr3-Tbx1 interactions\u00a0 in brain vascular development\u00a0\u00a0 Journal of Vascular Research , 2019 ISSN 1018-1172 ; WOS:000463529300105 3rd Joint Meeting of the European Society for Microcirculation (ESM) and the European Vascular Biology Organization (EVBO). Maastricht.<\/p>

    Parisot J* and Flore G*,<\/strong> Bertacchi M, Studer M.( *Equal Contributors)COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 1;144(11):2045-2058. doi: 10.1242\/dev.139949. Epub 2017 May 15.\u00a0 ISSN 0950-1991; WOS:000402276800015; scopus: 2-s2.0-85020129316<\/p>

    Flore G<\/strong>, \u00a0Cioffi S, Bilio M, Illingworth E.\u00a0 Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome. Cereb. Cortex. 2017 Mar 1;27(3):2210-2225. doi: 10.1093\/cercor\/bhw076.ISSN 1047-3211; WOS:000397636600041; Scopus: 2-s2.0-85009456121<\/p>

    Cioffi S., Turturo MG., Martucciello S.,\u00a0 Flore G<\/strong>., Baldini A.,\u00a0 Illingworth E. (2017).Vegfr3 overexpression partially rescues the brain vascular defects of Tbx1 mutants.\u00a0 Journal of Vascular Research , 2017 ISSN 1018-1172; WOS:000402740200175 2nd Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO). Gen\u00e8ve<\/p>

    Flore G<\/strong>, Di Ruberto G, Parisot J, Sannino S, Russo F, Illingworth EA, Studer M, De Leonibus E. Gradient COUP-TFI Expression Is Required for Functional Organization of the Hippocampal Septo-Temporal Longitudinal Axis. Cereb. Cortex. 2017 Feb 1;27(2):1629-1643. doi:10.1093\/cercor\/bhv336.ISSN 1047-3211 ; WOS:000397257600058; Scopus: 2-s2.0-85020124536<\/p>

    De Cegli R., Iacobacci S., Flore G<\/strong>., Gambardella G., Mao L.,\u00a0 Cutillo L.,\u00a0\u00a0 Lauria M., Klose J., Illingworth E., Banfi S., and Diego di Bernardo Reverse-engineering a mouse embryonic stem-cell specific transcriptional network reveals a new modulator of neuronal differentiation \u2013 Nucleic Acid Research, (2013) Jan. vol.41 ( 2) :711-726 doi: 10.1093\/nar\/gks1136. Epub 2012 Nov 23.PMID: 23180766 ISSN 0305-1048 ; WOS:000314121100011;Scopus: 2-s2.0-84875477980<\/p>

    Romano A.L., Parisot\u00a0 J., Flore G.,<\/strong> Studer M. (2012).REGULATION OF EMBRYONIC AND ADULT NEURAL STEM CELLS DURING MOUSE CORTICOGENESIS; INVITED SPEAKERS.: CELL JOURNAL (YAKHTEH)\u00a0 2012 ,1,1; Vol 14 n.1 pag 18-18 ISSN\u00a0 2228-5806<\/p>

    Flore G.<\/strong> ,\u00a0 Sannino S., Russo F., Studer M., De Leonibus E. Dissociation between recent and remote memory: a lesson from mutant mice with dimorphic cortical regions .Genes,Brain and Behaviour\u00a0 02\/06\/2011 vol 10\u00a0 n.4\u00a0 ISSN 1601-183X 13 th annual meeting IBANGS- International behavioural and neural genetic society\u201c Genes,Brain and Behaviour\u201d, 10-14 May 2011, Rome<\/p>

    Alfano C.,\u00a0 Viola L.,\u00a0 Ik-Tsen Heng J., Pirozzi M., Clarkson M.,\u00a0 Flore G.,<\/strong> De Maio A., Schedl A.,\u00a0 Guillemot F. and Studer M. COUP-TFI promotes\u00a0 radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression\u00a0 – Development\u00a0 2011 Nov;138(21):4685-97 doi: 10.1242\/dev.068031. Epub 2011 Sep 28.PMID: 21965613 ISSN 0950-1991; WOS:000296060100012; Scopus: 2-s2.0-80053951528<\/p> <\/div>\n\t\t \n

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    POSITIONS HELD:<\/p>

    2018-12-27 to present | Research Scientist\u00a0 III level (Neurodevelopmental Pathologies and Pharmacological Trials)<\/strong> Institute of Genetics and Biophysics, Adriano Buzzati Traverso”, National Council of Research (CNR)- Department of Biochemical Science (DSB): Naples, Campania, IT<\/strong><\/p>

    2017-05-22 to 2018-12-27 | Temporary Researcher <\/strong>at Institute of Genetics and Biophysics, Adriano Buzzati Traverso”, National Council of Research (CNR): Naples, Campania, IT. – Prof.Baldini A. Lab, Full Professor at Federico II University , Naples, IT ( Pharmacological Rescue in 22q11.2 DGS<\/strong> )<\/p>

    2010-01 to 2017-05-21 | Post-DOC and Research fellow <\/strong>at \u00a0Institute of Genetics and Biophysics, Adriano Buzzati Traverso”, National Council of Research (CNR): Naples, Campania, IT\u00a0 – Prof. Elizabeth A. Illingworth\u00a0 Lab, Full Professor at Universit\u00e0 degli Studi di Salerno, IT ( Neural Development in 22q11.2 DGS<\/strong>)<\/p>

    2005-11-08 to 2009-12-31 | PhD student <\/strong>at Dr. Mich\u00e8le Studer’s Lab, ( Brain Development<\/strong>), Telethon Institute of Genetics and Medicine: Napoli, Campania, IT<\/strong><\/p>

    2003-10-01 to 2005-06-30 | Fellow<\/strong> at Dr.E.I. Rugarli’s Lab ( Neurodegeneration<\/strong> ) Telethon Institute of Genetics and Medicine: Napoli, Campania, IT<\/p>

    EDUCATION and QUALIFICATIONS:<\/p>

    Education:<\/p>

    2021-04-13 to 2022-07-26 | Second Level Master Degree in Preclinical and Clinical Drug Development and post marketing surveillance<\/u><\/strong> (Department of Pharmacy, School of Medicine and Surgery) \u2013 110\/110 com Laude<\/p>

    University of Naples Federico II: Naples, Campania, IT<\/p>

    2020-01-16 to 2020-06-25 | Advanced Training Course in Design, Project Management and Reporting of European Community Funds<\/strong> for Public Administration . University of Cassino and Southern Lazio: Cassino, Lazio, IT\u00a0 in join with PFORM-Advanced Management Training School and Funded by INPS- National Institute of Public Welfare<\/p>

    2005-11-08 to 2010-03-16 | PhD in Molecular Medicine – Human Genetics<\/u><\/strong>. \u00a0European School of Molecular Medicine: Milano, Lombardia, IT\u00a0 in join with Universit\u00e0 Federico II, Naples,IT \u00a0and Universit\u00e0 Statale, Milan, IT)<\/p>

    2005-10-20 to 2005-10-26 | Advanced Training Course in Scientific and Technological Research Career Development<\/strong> (P.O.R. 2000-2006) Regione Campania: Naples, Campania, IT<\/p>

    1997-10-01 to 2002-12-18 | Master’s Degree in Pharmacy – 14\/S Class of Master’s Degree in Pharmacy and Industrial Pharmacy<\/u><\/strong> (Department of Pharmacy School of Medicine and Surgery) University of Naples Federico II: Naples, Campania, IT.\u00a0 110\/110 cum Laude.<\/p>

    Qualifications:<\/p>

    2005-06-28 to present | National Suitability as Executive Pharmacist<\/strong> . Regione Umbria: Perugia, Umbria, IT<\/p>

    2003-07-27 to present | National Suitability as Professional Pharmacist<\/strong> (State Exams Office) University of Naples Federico II: Naples, Campania, IT<\/p>

    INTERNATIONAL CONFERENCES:<\/strong><\/p>

    • 2022|SIGU XX Congress (Italian Society of Human Genetics )Trieste , IT<\/li>
    • 2019|3rd<\/sup> Joint Meeting of the European Society for Microcirculation (ESM) and the European Vascular Biology Organization (EVBO). Maastricht, Netherlands<\/li>
    • 2017| 2nd Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO).Gen\u00e9ve , Switzerland.<\/li>
    • 2017| Cardiovascular Development Meeting 2017. Padova, IT<\/li>
    • 2016| Newcastle Cardiovascular Development Meeting ,Newcastle, England<\/li>
    • 2016|ABCD Meeting Salerno , IT<\/li>
    • 2014| 9th FENS forum of Neuroscience, Milano, IT<\/li>
    • 2014|ABCD Congress: \u201cStem Cells, development and regenerative Medicine\u201d, Salerno 6-7 Giugno 2014<\/li>
    • 2012| 1st Copenhagen Bioscence Conferences \u201cThe stem cell niche-development and disease\u201dCopenhagen, Denmark.<\/li>
    • 2011| XVI Convention Telethon, Riva del Garda, IT<\/li>
    • 2011| 13 th annual meeting IBANGS- International behavioural and neural genetic society\u201c Genes,Brain and Behaviour\u201d,Rome<\/li>
    • 2011|ABCD 2011 Congress, Ravenna, IT<\/li>
    • 2007|Meeting Adult Neurogenesis-Max Planck Institute for molecular cell Biology and Genetics, Dresden, Germany<\/li>
    • 2007|ABCD Congress , Rome, IT<\/li>
    • 2007| Telethon Convention, Salsomaggiore Terme, IT<\/li>
    • 2006| Federation of Life sciences -FISV meeting 2006- Gene Regulation and signaling in neural development. Riva del Garda. IT<\/li>
    • 2005|Second Meeting on the Molecular Mechanism of Neurodegeneration, , Milano , IT<\/li>
    • 2005| Telethon Convention, Salsomaggiore Terme, IT<\/li><\/ul>

      FUNDINGS-Part of:<\/p>

      Fondation LEDUCQ, 15CVD01 ( PI and European Coordinator Prof. Baldini) 01\/01\/2016 – 31\/12\/2020- extension to 2022: “22q11.2 deletion syndrome: Novel approaches to understand cardiopharyngeal pathogenesis”, approx. US$900.000 for the Unit.<\/p>

      Jerome Lejeune Fondation: Vitamin B12 treatment of mouse models of DiGeroge syndrome: is it effective for the brain phenotype.( PI Elizabeth Illingworth)\u00a0 Period of award,\u00a0 01-02-2018 \u2013 31-01-2020.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Total Costs: Euros 40,000<\/p>

      MIUR PRIN 20179J2P9J 2017-2019 (Prof. Baldini Unit Coordinator), 2017-2019: \u201cUnraveling cardiac progenitor biology: in vivo mechanistic insights and significance for congenital heart disease\u201d (approx. \u20ac300.000 to Unit)<\/p>

      Telethon Foundation GGP14211 (Prof. Baldini P.I.), 2015-2018: “Phenotypic rescue of the DiGeorge syndrome phenotype in mouse models” (\u20ac341.600).<\/p>

      AIRC IG-17529 (Italian Association for Cancer Research), Prof. Baldini P.I. “p53-Tbx1 interaction in development and cell differentiation”. 2016 – 2019, total funded: \u20ac 228.000<\/p>

      Telethon Project GGP14211 , 2015-2018: Telethon Foundation “Phenotypic rescue of the DiGeorge syndrome phenotype in mouse models” 22\/5\/2017- 21\/05\/2019; ( Prof. E.A. Illingworth P.I) \u00a0Total funded : 341.600,00 euro<\/p>

      Ministry of Health RF-2011- 02347197 (Prof. Baldini P.I.) “Epidrugs and cardiac differentiation: relevance for the 22q11.2 deletion syndrome” (2014-2017, approx \u20ac292.609).<\/p>

      EU-FP7 CardioGeNet Program (Prof. Baldini P.I. and Coordinator) 2009-2013: \u201cDefinition of a genetic network involved in congenital heart disease\u201d (Approx. \u20ac600.000 to Unit).<\/p>

      MIUR (Italian Ministry of University and Research) PON 01_02342, 2011-2015. Prof. Baldini, Scientific Coordinator. \u201cRegenerative medicine and tissue engineering: Novel approaches to damaged tissue repair\u201d. (approx \u20ac1.000.000 to Unit).<\/p>

      MIUR ” Quality FareBio: Stem Cell Reprogramming Laboratory\u201d 2011-2013. Prof. Baldini Responsabile Unit\u00e0 IGB-CNR (approx \u20ac120.000 to Unit)<\/p>

      MIUR PRIN 2009J7F5WA (Prof. Baldini Responsabile Unit\u00e0), 2011-2013: \u201cTbx1: Functional Mechanisms and interactions with chromatin\u201d (approx. \u20ac150.000).<\/p>

      Telethon Foundation GGP11029 (Prof. Baldini P.I.), 2011-2014: \u201cPhenotypic variability and gene haploinsufficiency\u201d (Approx. \u20ac330.000).<\/p>

      MIUR (Italian Ministry of University and Research) PON 03PE_00060-7, 2013-2015. Unit\u00e0 IGB-CNR. \u201cPreclinical development of new therapies and innovative strategies for the production of molecules with pharmacological action\u201d (approx. \u20ac450.000).<\/p>

      Project n. S04006 AIRM\u00a0 (S04006TELA- TELB) “Identification Of Genes Causing Schizophrenia–Related Behavior In A Mouse Model Of Del22q11 Syndrome” (Prof. E.A. Illingworth, P.I);\u00a0 01\/01\/2010- 30\/11\/2012<\/p>

      Telethon Foundation-\u00a0 <\/strong>FIRB Project \u201c Gene expression profiling\u00a0 of neural development and differentiation \u00a0\u201c(FIRB) n. TMSP27FIRG ( PI Dr. Michele Studer) 2005-2006<\/p>

      Telethon Foundation Project TERP08MDAB , \u201cHereditary Spastic paraplegia- Complicated Form\u201d (E.I. Rugarli ,PI)2003-2005<\/p>

      FUNDINGS-Self:<\/p>

      Salary awards:<\/p>

      15\/03\/2021 : Public selection call – one year scholarship for \u00a0II level Master Degree in “Preclinical and Clinical Drug Development and Post-marketing surveillance ” Federico II University , Department of Pharmacy – School of Medicine and Surgery, Naples \u2013IT<\/p>

      02\/05\/2017: \u00a0Public selection call -one year salary award as\u00a0 Temporary Researcher (TD)\u00a0 pursuant to article 23 of the D.P.R. 12\/2\/91 n.171 referred to in the Notice n. ICB-TD-24\/2017, prot. 0000444 of 02\/03\/2017, published in the Italian Official Gazette IV Special Series n. 13 of 02\/17\/2017 for position T.D. , Researcher profile, level III . Institute of Genetics and Biophysics, \u201cAdriano Buzzati Traverso”, National Council of Research (CNR)- Department of Biochemical Science(DSB): Naples, Campania, IT<\/p>

      8\/11\/2005: Public selection call \u2013Four year \u00a0scholarship awarded by the SEMM Doctoral School – III Cycle in agreement with the University of Naples Federico II (XXI Doctoral Cycle) and the University of Milan attended at the TIGEM – Telethon Institute of Genetics and Medicine ,Naples, IT<\/p>

      20\/10\/2005 :Public selection call for \u00a0Integrated Higher Education Path “Career development path in Scientific and Technological Research” Issued by: Campania Region, P.O.R. 2000-2006 : “Promotion of female participation in the labor market” code 13 Axis III Measure 3.14 Action E.2.1, IT<\/p>

      Institutional Animal Care and Use Committee Projects \u2013\u00a0 Part of<\/u><\/p>

      \u00a0<\/u><\/p>

      Title: “Pathogenetical studies on mouse models of DiGeorge Syndrome\u201d<\/p>

      Start date:\u00a0 2022 End date: 2027 Authorization N. 28\/2022-PR<\/p>

      Head researcher : Antonio Baldini, Experimental Executor: Antonio Baldini and Gemma Flore<\/p>

      Title: \u201c T-box TFs role \u00a0in neural and cardiac development\u201d<\/p>

      Start date:\u00a0 2016 End date: 2022 Authorization N. 257\/2016-PR<\/p>

      Head researcher: Antonio Baldini Experimental Executor: Antonio Baldini and Gemma Flore<\/p>

      DISTINCTIONS: <\/u><\/p>

      Cash prizes:\u00a0\u00a0<\/p>

      28\/06\/2008: \u20ac 1500,00 (third prize ) 14th N. Pascale International Scientific Prize for new projects:<\/p>

      Title: Bernacchia A* and\u00a0 Flore G*; Eshes S., Martinelli P., Langer T and Rugarli E.I. \u201cParaplegin deficiency in mitochondria causes neurodegeneration without general respiratory impairment\u201d. (*equal contribution)<\/p>

      18\/11\/2005: \u00a0\u20ac 3550,00 P.O.R. Voucher conferred by the Campania Region, to be used in transversal Professional Training Courses<\/p>

      Non-cash prizes:<\/p>

      25\/10\/2006: Best Poster Competition (II prize) conferred by Scientific Committee at \u00a0Telethon Institute of Genetics and Medicine Scientific Retreat 2006- Perugia.IT<\/p>

      Professional \u00a0Organizations\u00a0 Membership:<\/p>

      SINS \u2013 Italian Society of Neurosciences<\/p>

      FENS- Federation of European Neuroscience Societies<\/p>

      ALBA Network<\/p>

      SIDRI- Italian Society of PhD<\/p>

      NBG – Neapolitan Brain Group<\/p>

      ESC – European Society of Cardiology<\/p>

      FOFI- Professional Association of Pharmacists, Naples, IT: \u00a0\u00a019\/2\/2007- 2011 \u00a0Scientific Committee member for Quality in Pharmacy <\/u><\/p> <\/div>\n\t\t <\/div>\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

      Gemma Flore Researcher +39 081 6132226 \u00a0 gemma.flore@igb.cnr.it Embryonic Development and Biology of Stem Cells Keywords: : neurodevelopmental disorders, genetic rare diseases, mouse models, preclinical drug trials,\u00a0 22q11.2DS, TBX1 \u00a0 Research Interest Selected Publications Professional Experience My general research interest is in investigating neurodevelopmental disorders in rare diseases, through genetically engineered mouse models. In the […]<\/p>\n","protected":false},"author":82,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-10286","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/10286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/82"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=10286"}],"version-history":[{"count":43,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/10286\/revisions"}],"predecessor-version":[{"id":18974,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/10286\/revisions\/18974"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=10286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}