{"id":2493,"date":"2021-03-02T13:10:33","date_gmt":"2021-03-02T12:10:33","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=2493"},"modified":"2023-09-20T14:38:40","modified_gmt":"2023-09-20T12:38:40","slug":"marina-ciullo","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/marina-ciullo\/","title":{"rendered":"Marina Ciullo"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2493\" class=\"elementor elementor-2493\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dcc9420 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dcc9420\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-fc4fe83\" data-id=\"fc4fe83\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-23b16bb0 elementor-widget elementor-widget-bdt-member\" data-id=\"23b16bb0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"bdt-member.bdt-phaedra\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"bdt-member skin-phaedra bdt-transition-toggle\">\n\t\t\t\n\t\t\t\t<div class=\"bdt-member-photo-wrapper\">\n\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"bdt-member-photo\">\n\t\t\t\t\t\t<div class=\"\">\n\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/10\/DSC_0319.jpg\" title=\"DSC_0319\" alt=\"DSC_0319\" loading=\"lazy\" \/>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t<div class=\"bdt-member-overlay bdt-overlay-default bdt-position-cover bdt-transition-fade bdt-position-z-index\">\n\t\t\t\t<div class=\"bdt-member-desc bdt-position-center bdt-text-center\">\n\t\t\t\t\t<div class=\"bdt-member-content bdt-transition-slide-top-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-611590af\" data-id=\"611590af\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-52917e elementor-widget elementor-widget-heading\" data-id=\"52917e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Marina Ciullo<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-637962e8 elementor-widget elementor-widget-spacer\" data-id=\"637962e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-165c8c7e elementor-widget elementor-widget-text-editor\" data-id=\"165c8c7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong><span style=\"color: #006293;\">Research Director<\/span><\/strong><\/h3><div><p><strong>\u00a0<img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/> +39 081 6132251 \u00a0 <img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/> marina.ciullo@igb.cnr.it<\/strong><\/p><p><strong>Population Genetics and Genetic Epidemiology<\/strong><\/p><p><strong>Keywords: <\/strong>genomics, genetic epidemiology, population-based studies, inbreeding<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e83a3dd e-grid-align-left elementor-shape-rounded elementor-grid-0 elementor-widget elementor-widget-social-icons\" data-id=\"e83a3dd\" data-element_type=\"widget\" data-e-type=\"widget\" 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data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4f16d83b elementor-widget elementor-widget-eael-adv-tabs\" data-id=\"4f16d83b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-adv-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div data-scroll-on-click=\"no\" data-scroll-speed=\"300\" id=\"eael-advance-tabs-4f16d83b\" class=\"eael-advance-tabs eael-tabs-horizontal eael-tab-auto-active \" data-tabid=\"4f16d83b\">\n            <div class=\"eael-tabs-nav\">\n                <ul class=\"\" role=\"tablist\">\n                                            <li id=\"research-interest\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"research-interest-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Interest<\/span>                                                    <\/li>\n                                            <li id=\"selected-publications\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"selected-publications-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Selected Publications<\/span>                                                    <\/li>\n                                            <li id=\"professional-experience\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"professional-experience-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Professional Experience<\/span>                                                    <\/li>\n                                            <li id=\"research-group\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"research-group-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Group<\/span>                                                    <\/li>\n                                    <\/ul>\n            <\/div>\n            \n            <div class=\"eael-tabs-content\">\n\t\t        \n                    <div id=\"research-interest-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-interest-tab\">\n\t\t\t\t        <p>\u00a0<\/p><p>Our research interests are to identify genetic variants influencing complex phenotypes and to clarify how these variations affect gene function. The laboratory focuses on genetic studies of some isolated populations located in the Cilento region for which an extensive phenotype characterization as well as whole-genome genotyping and sequence-based data are available. Indeed, because of small number of founders and genetic drift, founder populations represent a powerful strategy for the discovery of low-frequency and rare variants involved in complex traits. Through the use of different isolated populations, deriving from diverse progenitors and sharing well defined environments and life habits, we aim to elucidate the genetics of the complex phenotypes caused by the interaction of multiple genes and the environment.\u00a0Our work on Cilento populations has also been contributing to international large-scale population-based genetic studies on a broad range of common phenotypes.<\/p><p>\u00a0<\/p><p>Genetic Park of Cilento and Vallo di Diano Project: <a href=\"http:\/\/www.igb.cnr.it\/cilento\">http:\/\/www.igb.cnr.it\/cilento<\/a><\/p><p>Cilento biobank:\u00a0<a href=\"https:\/\/www.igb.cnr.it\/index.php\/centro-risorse-biologiche\/\"> http:\/\/www.igb.cnr.it\/igb\/index.php\/centro-risorse-biologiche\/<\/a><\/p><p>\u00a0<\/p><p>Some ongoing studies:<\/p><p>\u00a0<\/p><ul><li><em>Human knockouts study in Cilento isolates<\/em><\/li><\/ul><p>Natural \u2018human knockouts\u2019 (HKOs) are referred to people carrying biallelic loss-of-function (LoF) mutations that disrupt both copies of a given gene. Phenotypic analyses of such HKO can provide insight into gene function. LoF variants tend to be significantly enriched in founder populations making these populations particularly adapt for HKO studies. Exome sequencing data and in-depth phenotypic assessment of Cilento populations are used to understand the phenotypic consequences of natural gene KO in humans.<\/p><p><strong>\u00a0<\/strong><\/p><ul><li><em>Clinical Relevance of a Widespread NOTCH3 Mutation for CADASIL Pathogenesis<\/em><\/li><\/ul><p>An inherited blood vessel disease called cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (or otherwise known as CADASIL) can cause impaired blood flow in brain blood vessels.\u00a0 CADASIL is caused by mutations in <em>NOTCH3<\/em> gene, which codes for a transmembrane receptor involved in the protection of \u00a0the structure of blood vessel walls. However, abnormal genetic variations of <em>NOTCH3<\/em> may generate proteins that do not have the protective abilities and can be associated with blood vessel damage and cognitive impairment. Studying a Cilento population, we have recently discovered that the cysteine-altering p.Arg1231Cys mutation in <em>NOTCH3<\/em> is present in a large number of subjects all included in a big pedigree so, making this population an invaluable resource to improve the knowledge of CADASIL pathogenesis. Our study aims to understand how the p.Arg1231Cys mutation may impact the development of CADASIL and whether other genetic factors may be involved in the disease. The study results may provide further insights into the underlying biology of CADASIL, and, ultimately, an increased understanding of the relationship between blood vessel disorders and dementia.<\/p>                    <\/div>\n\t\t        \n                    <div id=\"selected-publications-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"selected-publications-tab\">\n\t\t\t\t        <p><u>Genetics of PlGF plasma levels highlights a role of its receptors and supports the link between angiogenesis and immunity.<\/u> Ruggiero D, Nutile T, Nappo S, Tirozzi A, Bellenguez C, Leutenegger AL, Ciullo M. <strong><em>Sci Reports<\/em><\/strong> 2021 Aug 19;11(1):16821. doi: 10.1038\/s41598-021-96256-0.<\/p><p><u>The power of genetic diversity in genome-wide association studies of lipids. <\/u>Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, et al\u00a0 (including Ciullo M) <strong><em>Nature<\/em><\/strong><em>.<\/em> 2021 Dec;600(7890):675-679. doi: 10.1038\/s41586-021-04064-3. Epub 2021 Dec 9.<\/p><p><u>Whole-Exome Sequencing in the Isolated Populations of Cilento from South Italy.<\/u> Nutile T, Ruggiero D, Herzig AF, Tirozzi A, Nappo S, Sorice R, Marangio F, Bellenguez C, Leutenegger AL, and Ciullo M. <strong><em>Sci Reports<\/em><\/strong> 2019 Mar 11;9(1):4059. doi: 10.1038\/s41598-019-41022-6<\/p><p><u>Associations of autozygosity with a broad range of human phenotypes.<\/u> Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, et al (including Ciullo M). <strong><em>Nat Commun.<\/em> <\/strong>2019 Oct 31;10(1):4957. doi: 10.1038\/s41467-019-12283-6<\/p><p><u>Detecting the dominance component of heritability in isolated and outbred human populations.<\/u> Herzig AF, Nutile T, Ruggiero D, Ciullo M*, Perdry H, Leutenegger AL. <strong><em>Sci Reports <\/em><\/strong>2018 Dec 21;8(1):18048. doi: 10.1038\/s41598-018-36050-7.<\/p><p><u>Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.<\/u> Choi SH, Ruggiero D, Sorice R, Song C, Nutile T, Vernon Smith A, Concas MP, Traglia M, Barbieri C, Ndiaye NC, Stathopoulou MG, Lagou V, Maestrale GB, Sala C, Debette S, Kovacs P, Lind L, Lamont J, Fitzgerald P, T\u00f6njes A, Gudnason V, Toniolo D, Pirastu M, Bellenguez C, Vasan RS, Ingelsson E, Leutenegger AL, Johnson AD, DeStefano AL, Visvikis-Siest S, Seshadri S, Ciullo M. <strong><em>PLoS Genetics<\/em> <\/strong>2016 Feb 24;12(2):e1005874.<\/p><p><u>Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.<\/u> Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, et al. (including Ciullo M). <strong><em>Nat Commun<\/em>. <\/strong>2016 Jan 21;7:10023.<\/p><p><u>Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.<\/u> Kato N, Loh M, Takeuchi F, Verweij N, Wang X, et al. (including Ciullo M). <strong><em>Nat Genetics<\/em><\/strong> 2015 Sep 21.<\/p><p><u>Directional dominance on stature and cognition in diverse human populations<\/u>. Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T et al. (including Ciullo M) &#8211; <strong><em>Nature<\/em><\/strong> 2015 July 1.<\/p><p><u>Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.<\/u> Genetics of personality consortium, et al (including Ciullo M). <strong><em>JAMA Psychiatry<\/em>.<\/strong> 2015 Jul 1;72(7):642-50.<\/p><p><u>Genetic Variants modulating CRIPTO Serum Levels identified by Genome-Wide Association Study in Cilento Isolates<\/u><strong>.<\/strong> Ruggiero D, Nappo S, Nutile T, Sorice R, Talotta F, Giorgio E, Bellenguez C, Leutenegger AL, Liguori G L, Ciullo M. <strong><em>PloS Genetics.<\/em><\/strong> 2015 Jan 28;11(1):e1004976. doi: 10.1371\/journal.pgen.1004976. eCollection 2015 Jan.<\/p><p><u>Angiogenesis and biomarkers of cardiovascular risk in adults with metabolic syndrome.<\/u> Siervo M, Ruggiero D, Sorice R, Nutile T, Aversano M, Stephan BC, Ciullo M. <strong><em>J Intern Med<\/em>.<\/strong> 2010 Oct;268(4):338-47. doi: 10.1111\/j.1365-2796.2010.02255.x.<\/p><p><u>Genome-Wide Association Analyses Identify 18 New Loci Associated With Serum Urate.<\/u> K\u00f6ttgen, E. Albrecht, A. Teumer, V. Vitart, J. Krumsiek, C. Hundertmark, G. Pistis, D. Ruggiero, C.M O\u2019Seaghdha, T. Haller et al (including M. Ciullo as co-last author) <strong><em>Nat Genetics<\/em> <\/strong>2013 Feb;45(2):145-54. doi: 10.1038\/ng.2500. Epub 2012 Dec 23<\/p><p><u>75 genetic loci influencing the human red blood cell.<\/u> P. van der Harst, W. Zhang, I. V Mateo Leach, J. Sehmi, N. Verweij, D. S Paul, A. Rendon, H. Allayee, X. Li, A. Radhakrishnan, S.-T. Tan, C. A Albers, A. Al-Hussani, F.W Asselbergs, M. Ciullo et al. <strong><em>Nature<\/em><\/strong>. 2012 Dec 20;492(7429):369-75. doi: 10.1038\/nature11677. Epub 2012 Dec 5.<\/p><p>The complete list of publications is available on Google Scholar (Marina Ciullo profile) and at ORCID ID: orcid.org\/0000-0002-9621-9984<\/p>                    <\/div>\n\t\t        \n                    <div id=\"professional-experience-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"professional-experience-tab\">\n\t\t\t\t        <p>Marina Ciullo is Research Director of National Research Council of Italy at Institute of Genetics and Biophysics &#8220;A. Buzzati-Traverso&#8221; (IGB-CNR) of Naples, Italy. She obtained a degree in Biological Sciences at University &#8220;Federico II&#8221; of Naples in 1993. She got a PhD in Biology at the University of Paris (Paris XI), France in 2003 working on chromosomal instability in cancer at the Unit\u00e9 de G\u00e9nomique Fonctionnelle Biologie Syst\u00e9mique pour la Sant\u00e9-CNRS, in Villejuif. As postdoc at IGB-CNR she acquired expertise in human genetics and molecular genetics. She was visiting Researcher at the Unit\u00e9 G\u00e9n\u00e9tique Epid\u00e9miologique et Structure des Populations humaines &#8211; INSERM, Paris, France between 2004 to 2006. In that period, she expanded her expertise in genetic epidemiology. Since 2007 she is the head of the Genetics of Complex traits laboratory at the IGB-CNR and scientific coordinator of the \u201cGenetic Park of Cilento and Vallo di Diano\u201d project, one of the largest genetic epidemiology studies in Italy on isolated populations. She leads a research group working on population data collection, statistical and molecular analyses. Moreover, she has established strong ties with local communities that have made it possible to recruit and track participants to Cilento project over time (http:\/\/www.igb.cnr.it\/cilento). She has coordinated and\/or participated in many GWAS meta-analysis studies in large population cohorts working together with international groups and in a multidisciplinary context. She is member of the Steering Committee in several International Consortia and is one of the co-founders of the VEGF Consortium. She has attracted several grants from National and International funding Agencies, including EU programmes, Alzheimer\u2019s Association, and Italian Ministry of University and Research (MUR). She serves as reviewer for a number of scientific journals and is author of more than 70 peer-reviewed publications.<\/p>                    <\/div>\n\t\t        \n                    <div id=\"research-group-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-group-tab\">\n\t\t\t\t        <p><div class=\"tmm tmm_research-group-ciullo\"><div class=\"tmm_2_columns tmm_wrap tmm_plugin_f\"><span class=\"tmm_two_containers_tablet\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.igb.cnr.it\/index.php\/daniela-ruggiero\/\" title=\"Daniela Ruggiero\"><div class=\"tmm_photo tmm_pic_research-group-ciullo_0\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/11\/images.png); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><\/a><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Daniela<\/span> <span class=\"tmm_lname\">Ruggiero<\/span><\/div><div class=\"tmm_job\">Researcher<\/div><div class=\"tmm_desc\" style=\"text-align:\"><p>&nbsp;<img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/>&nbsp;+39 081 6132 358&nbsp; &nbsp;&nbsp;<img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/>&nbsp;daniela.ruggiero@igb.cnr.it<\/p><p><strong>Population Genetics and Genetic Epidemiology<\/strong><\/p><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.igb.cnr.it\/index.php\/teresa-nutile\/\" title=\"Teresa Nutile\"><div class=\"tmm_photo tmm_pic_research-group-ciullo_1\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/10\/DSC_0151.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><\/a><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Teresa<\/span> <span class=\"tmm_lname\">Nutile<\/span><\/div><div class=\"tmm_job\">Technologist<\/div><div class=\"tmm_desc\" style=\"text-align:\"><div class=\"elementor-element elementor-element-7aeea399 elementor-widget elementor-widget-text-editor\" data-id=\"7aeea399\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-text-editor elementor-clearfix\"><div><p>&nbsp;&nbsp;<img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/>&nbsp;+39 081 6132 358&nbsp;<img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/>&nbsp;teresa.nutile@igb.cnr.it<\/p><p><strong>Population Genetics and Genetic Epidemiology<\/strong><\/p><p><strong>Keywords:&nbsp;<\/strong>Bioinformatics, Genetic epidemiology, Complex Traits, Founder Populations<\/p><\/div><\/div><\/div><\/div><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><span class=\"tmm_two_containers_tablet\"><\/span><\/div><span class=\"tmm_columns_containers_desktop\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><div class=\"tmm_photo tmm_pic_research-group-ciullo_2\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/11\/images.png); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Pasqualina<\/span> <span class=\"tmm_lname\">Cennamo<\/span><\/div><div class=\"tmm_job\">PhD student (Italian Ministry of University and Research (MUR) funded)<\/div><div class=\"tmm_desc\" style=\"text-align:\"><p><img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/> pasqualina.cennamo@igb.cnr.it<\/p><p><strong>Project title:<\/strong> <em>Systemic oxidative state and neurodegeneration<\/em><\/p><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><div class=\"tmm_photo tmm_pic_research-group-ciullo_3\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/11\/images.png); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Monica<\/span> <span class=\"tmm_lname\">Apostolico<\/span><\/div><div class=\"tmm_job\">Undergraduate student<\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div style=\"clear:both;\"><\/div><\/div><\/div><\/div><\/p>                    <\/div>\n\t\t                    <\/div>\n        <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Marina Ciullo Research Director \u00a0 +39 081 6132251 \u00a0 marina.ciullo@igb.cnr.it Population Genetics and Genetic Epidemiology Keywords: genomics, genetic epidemiology, population-based studies, inbreeding Orcid Research Interest Selected Publications Professional Experience Research Group \u00a0 Our research interests are to identify genetic variants influencing complex phenotypes and to clarify how these variations affect gene function. The laboratory focuses [&hellip;]<\/p>\n","protected":false},"author":22,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-2493","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/22"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=2493"}],"version-history":[{"count":19,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2493\/revisions"}],"predecessor-version":[{"id":16045,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2493\/revisions\/16045"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=2493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}