{"id":2499,"date":"2021-03-02T13:10:51","date_gmt":"2021-03-02T12:10:51","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=2499"},"modified":"2025-03-26T11:29:44","modified_gmt":"2025-03-26T10:29:44","slug":"sandro-de-falco","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/sandro-de-falco\/","title":{"rendered":"Sandro De Falco"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2499\" class=\"elementor elementor-2499\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63a5c1a6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"63a5c1a6\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-7f369d9d\" data-id=\"7f369d9d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-17ff53e1 elementor-widget elementor-widget-bdt-member\" data-id=\"17ff53e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"bdt-member.bdt-phaedra\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"bdt-member skin-phaedra bdt-transition-toggle\">\n\t\t\t\n\t\t\t\t<div class=\"bdt-member-photo-wrapper\">\n\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"bdt-member-photo\">\n\t\t\t\t\t\t<div class=\"\">\n\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Foto-1_Sandro-De-Falco.jpeg\" title=\"Foto 1_Sandro De Falco\" alt=\"Foto 1_Sandro De Falco\" loading=\"lazy\" \/>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t<div class=\"bdt-member-overlay bdt-overlay-default bdt-position-cover bdt-transition-fade bdt-position-z-index\">\n\t\t\t\t<div class=\"bdt-member-desc bdt-position-center bdt-text-center\">\n\t\t\t\t\t<div class=\"bdt-member-content bdt-transition-slide-top-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-561825b\" data-id=\"561825b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-449fdf45 elementor-widget elementor-widget-heading\" data-id=\"449fdf45\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Sandro De Falco<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d831699 elementor-widget elementor-widget-text-editor\" data-id=\"5d831699\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong><span style=\"color: #006293;\">Research Director<\/span><\/strong><\/h3><div><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/> +39 081 6132354\u00a0 <img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/> sandro.defalco@igb.cnr.it<\/strong><\/p><p><strong>Molecular Oncology<\/strong><\/p><p><strong>Keywords: <\/strong>Cardiovascular biology, Angiogenesis, Cancer, Ocular Neovascular Diseases, Drug Discovery and Delivery<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c631d5a e-grid-align-left elementor-shape-rounded elementor-grid-0 elementor-widget elementor-widget-social-icons\" data-id=\"c631d5a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-social-icons-wrapper elementor-grid\" role=\"list\">\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-orcid elementor-animation-grow-rotate elementor-repeater-item-884e7e5\" href=\"https:\/\/orcid.org\/0000-0002-6501-1697\" 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data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-36ba6c91 elementor-widget elementor-widget-eael-adv-tabs\" data-id=\"36ba6c91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-adv-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div data-scroll-on-click=\"no\" data-scroll-speed=\"300\" id=\"eael-advance-tabs-36ba6c91\" class=\"eael-advance-tabs eael-tabs-horizontal eael-tab-auto-active \" data-tabid=\"36ba6c91\">\n            <div class=\"eael-tabs-nav\">\n                <ul class=\"\" role=\"tablist\">\n                                            <li id=\"research-interest\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"research-interest-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Interest<\/span>                                                    <\/li>\n                                            <li id=\"selected-publications\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"selected-publications-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Selected Publications<\/span>                                                    <\/li>\n                                            <li id=\"professional-experience\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"professional-experience-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Professional Experience<\/span>                                                    <\/li>\n                                            <li id=\"research-group\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"research-group-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Group<\/span>                                                    <\/li>\n                                    <\/ul>\n            <\/div>\n            \n            <div class=\"eael-tabs-content\">\n\t\t        \n                    <div id=\"research-interest-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-interest-tab\">\n\t\t\t\t        <p>The research interests of the Angiogenesis Lab are focused on cardiovascular biology, mainly on the study of molecular mechanisms governing physiological and pathological angiogenesis, and on drug discovery devoted to inhibit pathological angiogenesis.<\/p><p>Biochemical and functional relationship of molecular factors involved in angiogenesis are studied using molecular and cellular biology approaches and functional genomics in mice.<\/p><p>Moreover, for these studies is crucial the availability at Angiogenesis Lab of in vivo disease models, such as syngeneic and xenograft tumors, corneal and choroid neovascularization, hind limb ischemia.<\/p><p>In the last ten years, the research activities of Angiogenesis Lab have been granted by Horizon 2020, AIRC, Telethon, government agencies (MIUR, MISE, Campania Region) and from national and foreign companies (Bayer, Abbott, Thromb-X, Multimedica, BIOVIIIx).<\/p><p>The studies on drug discovery has allowed the opportunity to co-found an innovative start up, named AnBition, which activities are focused on developing new molecules and technologies for treating or diagnosing angiogenesis-related diseases.<\/p><p>\u00a0<\/p><p>In the picture, the contribution of Angiogenesis Lab into unveil the important role of VEGF-A\/PlGF heterodimer in pathological angiogenesis.<\/p><p><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-12124 alignleft\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-1024x1024.png\" alt=\"\" width=\"531\" height=\"531\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-1024x1024.png 1024w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-768x768.png 768w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-1536x1536.png 1536w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-700x700.png 700w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract-510x510.png 510w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/graphical-abstract.png 1650w\" sizes=\"(max-width: 531px) 100vw, 531px\" \/><\/p><div class=\"notranslate\" style=\"all: initial;\">\u00a0<\/div>                    <\/div>\n\t\t        \n                    <div id=\"selected-publications-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"selected-publications-tab\">\n\t\t\t\t        <ul><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33918807\/\">Prolyl 3-Hydroxylase 2 Is a Molecular Player of Angiogenesis.<\/a> Pignata P, Apicella I, Cicatiello V, Puglisi C, Magliacane Trotta S, Sanges R, Tarallo V, <strong>De Falco S<\/strong>. <em>Int J Mol Sci<\/em>. <em>22:3896<\/em> (<strong>2021<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33640465\/\">VEGFR1 signaling in retinal angiogenesis and microinflammation.<\/a> Uemura A, Fruttiger M, D&#8217;Amore PA, <strong>De Falco S<\/strong>, Joussen AM, Sennlaub F, Brunck LR, Johnson KT, Lambrou GN, Rittenhouse KD, Langmann T. <em>Prog Retin Eye Res.<\/em> <em>Sep;84:100954<\/em> (<strong>2021<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31936463\/\">Oral Delivery of a Tetrameric Tripeptide Inhibitor of VEGFR1 Suppresses Pathological Choroid Neovascularization.<\/a> Tarallo V, Iaccarino E, Cicatiello V, Sanna R, Ruvo M, <strong>De Falco S<\/strong>. <em>Int J Mol Sci. 21:410 <\/em>(<strong>2020<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31406382\/\">Placental growth factor regulates the generation of T<sub>H<\/sub>17 cells to link angiogenesis with autoimmunity.<\/a> Yoo SA, Kim M, Kang MC, Kong JS, Kim KM, Lee S, Hong BK, Jeong GH, Lee J, Shin MG, Kim YG, Apicella I, Cicatiello V, <strong>De Falco S<\/strong>, Yoon CH, Cho CS, Ryoo ZY, Lee SH, Kim WU. <em>Nature Immunology 20:1348-1359<\/em> (<strong>2019<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29925004\/\">Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A.<\/a> Apicella I, Cicatiello V, Acampora D, Tarallo V, <strong>De Falco S<\/strong><em>.<\/em><em> Cell Rep. 23:3635-3646 <\/em>(<strong>2018<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28991230\/\">Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.<\/a> Di Ruocco F, Basso V, Rivoire M, Mehlen P, Ambati J,\u00a0<strong>De Falco S<\/strong>,\u00a0Tarallo V. <em>Oncogene 37:627-637<\/em> (<strong>2018<\/strong>)\u00a0<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28427198\/\">Hypoxia activates placental growth factor expression in lymphatic endothelial cells.<\/a> Tudisco L, Orlandi A, Tarallo V, <strong>De Falco S. <\/strong><em> 8:32873-32883<\/em> (<strong>2017<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26925256\/\">Intravenous immune globulin suppresses angiogenesis in mice and humans.<\/a> Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, <strong>De Falco S<\/strong>, Ambati J. <em>Signal Transduct Target Ther. 1:15002<\/em> (<strong>2016<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26918197\/\">Human IgG1 antibodies suppress angiogenesis in a target-independent manner.<\/a> Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, <strong>De Falco S<\/strong>, Ambati J. <em>Signal Transduct Target Ther. 1:15001<\/em>(<strong>2016<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25868854\/\">Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models.<\/a> Cicatiello V, Apicella I, Tudisco L, Tarallo V, Formisano L, Sandomenico A, Kim Y, Bastos-Carvalho A, Orlandi A, Ambati J, Ruvo M, Bianco R, De Falco S. <em>6:10563-76<\/em> (<strong>2015<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24574826\/\">Antiangiogenesis therapy: an update after the first decade.<\/a> <strong>De Falco S<\/strong>. Korean J Intern Med. 2014 1:1-11 (<strong>2014<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24504136\/\">Epigenetic control of hypoxia inducible factor-1\u03b1-dependent expression of placental growth factor in hypoxic conditions.<\/a> Tudisco L, Della Ragione F, Tarallo V, Apicella I, D&#8217;Esposito M, Matarazzo MR, <strong>De <\/strong><strong><em>Falco S<\/em><\/strong><em>. Epigenetics. <\/em><em>9:600-10 <\/em>(<strong>2014<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23139276\/\">Inhibition of choroidal and corneal pathologic neovascularization by Plgf1-de gene transfer.<\/a> Tarallo V, Bogdanovich S, Hirano Y, Tudisco L, Zentilin L, Giacca M, Ambati J, <strong>De Falco S<\/strong>. <em>Invest Ophthalmol Vis Sci. 53:7989-96<\/em> (<strong>2012<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22228176\/\">The discovery of placenta growth factor and its biological activity.<\/a> <strong>De Falco S.<\/strong> <em>Exp Mol Med. 44:1-9<\/em> (<strong>2012<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21471210\/\">The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.<\/a> Tarallo V, Lepore L, Marcellini M, Dal Piaz F, Tudisco L, Ponticelli S, Lund FW, Roepstorff P, Orlandi A, Pisano C, De Tommasi N, <strong>De Falco S<\/strong>. <em>J Biol Chem. 286:19641-51<\/em> (<strong>2011<\/strong>)<\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20145150\/\">A placental growth factor variant unable to recognize vascular endothelial growth factor (VEGF) receptor-1 inhibits VEGF-dependent tumor angiogenesis via heterodimerization.<\/a> Tarallo V, Vesci L, Capasso O, Esposito MT, Riccioni T, Pastore L, Orlandi A, Pisano C, De Falco S. <em>Cancer Res. 70:1804-13<\/em> (<strong>2010<\/strong>)<\/li><\/ul>                    <\/div>\n\t\t        \n                    <div id=\"professional-experience-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"professional-experience-tab\">\n\t\t\t\t        <p>Sandro De Falco joined the IGB as Research Scientist in 2001, in the group of Graziella Persico. In 2005 got the position of CNR-Senior Researcher and group leader of Angiogenesis Laboratory. In 2020 got the position of Research Director.<\/p><p>In 2000 got an EMBO short-term fellow at the Center for Transgene Research and Technology, KU Leuven, Belgium, in the group of Prof. Peter Carmeliet.<\/p><p>From 1994 to 2000 he was first Senior Scientist and successively Head of molecular and cellular biology laboratory at biotech Company Tecnogen S.C.p.A. (Piana di Monteverna, Caserta, Italy).<\/p><p>Previously he was post-doctoral fellow at Laboratoire de Biophysique, Museum National d&#8217;Histoire Naturelle, Paris, France in the laboratory of prof. Claude H\u00e9l\u00e8ne, and at Department of Biochemistry and Medical Biotechnology, Faculty of Medicine, University &#8220;Federico II&#8221;, Naples Italy.<\/p><p>He holds his PhD in Biochemical Sciences in 1990, and the degree in Biological Sciences in 1985, at University &#8220;Federico II&#8221; of Naples, Italy.<\/p><p>\u00a0<\/p>                    <\/div>\n\t\t        \n                    <div id=\"research-group-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-group-tab\">\n\t\t\t\t        <div class=\"tmm tmm_research-group-de-falco\"><div class=\"tmm_2_columns tmm_wrap tmm_plugin_f\"><span class=\"tmm_two_containers_tablet\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.igb.cnr.it\/index.php\/valeria-tarallo\/\" title=\"Valeria  Tarallo\"><div class=\"tmm_photo tmm_pic_research-group-de-falco_0\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/image1-scaled.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><\/a><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Valeria <\/span> <span class=\"tmm_lname\">Tarallo<\/span><\/div><div class=\"tmm_job\">Senior Researcher<\/div><div class=\"tmm_desc\" style=\"text-align:\"><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/><\/strong>+39 081 6132453\u00a0 <strong><img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/><\/strong> valeria.tarallo@igb.cnr.it<strong><br><\/strong><\/p><p><strong>Molecular Oncology<\/strong><\/p><p><strong>Project Title:<\/strong> <em>Alu<\/em> RNA as a potential regulator of human gastrointestinal cancer progression and metastatic dissemination<\/p><p><strong>Keywords: <\/strong>Alu RNAs, cancer, angiogenesis, AMD<\/p><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.igb.cnr.it\/index.php\/sara-magliacane-trotta\/\" title=\"Sara Magliacane Trotta\"><div class=\"tmm_photo tmm_pic_research-group-de-falco_1\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/DSC_0135.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><\/a><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Sara<\/span> <span class=\"tmm_lname\">Magliacane Trotta<\/span><\/div><div class=\"tmm_job\">Researcher<\/div><div class=\"tmm_desc\" style=\"text-align:\"><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/><\/strong>+39 081 6132601\u00a0 <strong><img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/><\/strong> sara.magliacanetrotta@igb.cnr.it<\/p><p><strong>Project Title:<\/strong> <em>Alu<\/em> RNA as a potential regulator of human gastrointestinal cancer progression and metastatic dissemination<\/p><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><span class=\"tmm_two_containers_tablet\"><\/span><\/div><span class=\"tmm_columns_containers_desktop\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><div class=\"tmm_photo tmm_pic_research-group-de-falco_2\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/DSC_0129.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Grazia<\/span> <span class=\"tmm_lname\">Mercadante<\/span><\/div><div class=\"tmm_job\">Lab Technician<\/div><div class=\"tmm_desc\" style=\"text-align:\"><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/><\/strong>+39 081 6132601\u00a0 <strong><img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/>\u00a0<\/strong>grazia.mercadante@igb.cnr.it<\/p><p><strong>Project Title:<\/strong> support for all the projects of the group<\/p><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div style=\"clear:both;\"><\/div><\/div><\/div><\/div>\n\n                    <\/div>\n\t\t                    <\/div>\n        <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Sandro De Falco Research Director +39 081 6132354\u00a0 sandro.defalco@igb.cnr.it Molecular Oncology Keywords: Cardiovascular biology, Angiogenesis, Cancer, Ocular Neovascular Diseases, Drug Discovery and Delivery Orcid Linkedin Research Interest Selected Publications Professional Experience Research Group The research interests of the Angiogenesis Lab are focused on cardiovascular biology, mainly on the study of molecular mechanisms governing physiological and [&hellip;]<\/p>\n","protected":false},"author":35,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-2499","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/35"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=2499"}],"version-history":[{"count":79,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2499\/revisions"}],"predecessor-version":[{"id":18186,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2499\/revisions\/18186"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=2499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}