{"id":2501,"date":"2021-03-02T13:10:55","date_gmt":"2021-03-02T12:10:55","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=2501"},"modified":"2023-09-20T14:50:20","modified_gmt":"2023-09-20T12:50:20","slug":"ingram-iaccarino","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/ingram-iaccarino\/","title":{"rendered":"Ingram Iaccarino"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\"Ingram\"\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t
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Ingram Iaccarino<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Researcher<\/span><\/strong><\/h3>

\"\" +39 081 6132449-451 \u00a0 \"\" ingram.iaccarino@igb.cnr.it<\/strong><\/p>

Molecular Oncology<\/strong><\/p>

Keywords: <\/strong>Lymphoma, Myc, lncRNAs, Tumor microenvironment<\/p>

\u00a0<\/strong><\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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  • \n \n \n \n Research Interest<\/span> <\/li>\n
  • \n \n \n \n Selected Publications<\/span> <\/li>\n
  • \n \n \n \n Professional Experience<\/span> <\/li>\n <\/ul>\n <\/div>\n \n
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    I am currently working in the section of haematopathology of the Institute of Pathology of the University of Kiel in Germany. I am mostly focusing on the analysis of coding and non-coding genes in the development of different types of B-cell lymphomas. We perform gene expression and mutational analyses as well as a number of in situ analyses on tissue biopsies, in order to associate particular changes either in tumor cells or in the microenvironment, to improve lymphoma classification as well as diagnosis and prognosis.<\/p> <\/div>\n\t\t \n

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    \u201cLncRNA as Cancer Biomarkers\u201d. Methods in Molecular Biology, vol 2348. (2021).<\/p>

    \u201cTumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1\u201d. Blood 136(25):2851-2863. (2020)<\/p>

    \u201cParacrine recruitment and activation of fibroblasts by c-Myc expressing breast epithelial cells through the IGFs\/IGF-1R axis\u201d. Int J Cancer 145(10):2827-2839. (2019)<\/p>

    \u201clncRNAs and MYC: An Intricate Relationship\u201d. International Journal of Molecular Sciences 18(7): E1497 (2017)<\/p>

    \u201cMINCR is a MYC-induced lncRNA able to modulate MYC\u2019s transcriptional network in Burkitt lymphoma cells.\u201d Proceedings of the National Academy of Sciences USA 112(38):E5261-70 (2015)<\/p>

    \u201cAnalysis of secretome changes uncovers an autocrine\/paracrine component in the modulation of cell proliferation and motility by c-Myc\u201d Journal of Proteome Research. 10(12):5326\u20135337 (2011)<\/p>

    \u201cPraf2 is a Novel Bcl-xL\/Bcl-2 Interacting Protein with the Ability to Modulate Survival of Cancer Cells\u201d. PLoS ONE 5(12):e15636 (2010)<\/p>

    \u201cModulation of cellular migration and survival by c-Myc through the down-regulation of urokinase (uPA) and uPA receptor.\u201d Molecular and Cellular Biology 30(7):1838-51 (2010)<\/p> <\/div>\n\t\t \n

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    I have a strong background as researcher in the fields of biochemistry, molecular biology and cell biology applied to cancer research. I am mainly interested in the understanding of the signal transduction events that drive oncogenic cellular transformation, through the modulation of both coding and non-coding RNAs.<\/p> <\/div>\n\t\t <\/div>\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    Ingram Iaccarino Researcher +39 081 6132449-451 \u00a0 ingram.iaccarino@igb.cnr.it Molecular Oncology Keywords: Lymphoma, Myc, lncRNAs, Tumor microenvironment \u00a0 Research Interest Selected Publications Professional Experience I am currently working in the section of haematopathology of the Institute of Pathology of the University of Kiel in Germany. I am mostly focusing on the analysis of coding and non-coding […]<\/p>\n","protected":false},"author":51,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-2501","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2501","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/51"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=2501"}],"version-history":[{"count":16,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2501\/revisions"}],"predecessor-version":[{"id":16070,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2501\/revisions\/16070"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=2501"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}