{"id":2515,"date":"2021-03-02T13:12:41","date_gmt":"2021-03-02T12:12:41","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=2515"},"modified":"2025-11-03T14:03:38","modified_gmt":"2025-11-03T13:03:38","slug":"valeria-tarallo","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/valeria-tarallo\/","title":{"rendered":"Valeria Tarallo"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2515\" class=\"elementor elementor-2515\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7dfd17b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7dfd17b\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-5555239\" data-id=\"5555239\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4e9cd0c6 elementor-widget elementor-widget-bdt-member\" data-id=\"4e9cd0c6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"bdt-member.bdt-phaedra\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"bdt-member skin-phaedra bdt-transition-toggle\">\n\t\t\t\n\t\t\t\t<div class=\"bdt-member-photo-wrapper\">\n\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"bdt-member-photo\">\n\t\t\t\t\t\t<div class=\"\">\n\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/11\/image1-scaled.jpg\" title=\"image1\" alt=\"image1\" loading=\"lazy\" \/>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t<div class=\"bdt-member-overlay bdt-overlay-default bdt-position-cover bdt-transition-fade bdt-position-z-index\">\n\t\t\t\t<div class=\"bdt-member-desc bdt-position-center bdt-text-center\">\n\t\t\t\t\t<div class=\"bdt-member-content bdt-transition-slide-top-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-71d31f54\" data-id=\"71d31f54\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6808c2d4 elementor-widget elementor-widget-heading\" data-id=\"6808c2d4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Valeria Tarallo<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c0c7e68 elementor-widget elementor-widget-spacer\" data-id=\"3c0c7e68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76e2893c elementor-widget elementor-widget-text-editor\" data-id=\"76e2893c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong><span style=\"color: #006293;\">Senior Researcher<\/span><\/strong><\/h3><div><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/> +39 081 6132 453 \u00a0\u00a0 <img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/> valeria.tarallo@igb.cnr.it<\/strong><\/p><p><strong>Molecular Oncology<\/strong><\/p><p><strong>Keywords: <\/strong>Alu RNAs, cancer, angiogenesis, AMD<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01f82ce e-grid-align-left elementor-shape-rounded elementor-grid-0 elementor-widget elementor-widget-social-icons\" data-id=\"01f82ce\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t<div 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data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-adv-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div data-scroll-on-click=\"no\" data-scroll-speed=\"300\" id=\"eael-advance-tabs-5e3714f7\" class=\"eael-advance-tabs eael-tabs-horizontal eael-tab-auto-active \" data-tabid=\"5e3714f7\">\n            <div class=\"eael-tabs-nav\">\n                <ul class=\"\" role=\"tablist\">\n                                            <li id=\"research-interest\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"research-interest-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Interest<\/span>                                                    <\/li>\n                                            <li id=\"selected-publications\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"selected-publications-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Selected Publications<\/span>                                                    <\/li>\n                                            <li id=\"professional-experience\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"professional-experience-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Professional Experience<\/span>                                                    <\/li>\n                                            <li id=\"research-group\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"research-group-tab\" aria-expanded=\"false\">\n                            \n                            \n                            \n                                                            <span class=\"eael-tab-title title-after-icon\" >Research Group<\/span>                                                    <\/li>\n                                    <\/ul>\n            <\/div>\n            \n            <div class=\"eael-tabs-content\">\n\t\t        \n                    <div id=\"research-interest-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-interest-tab\">\n\t\t\t\t        <p>The main research interests are the study of Alu RNAs in cancer progression and in the dry form of age-related macular degeneration and other pathological disorders and the study of molecular factors of VEGF family members and related receptors involved in physiological and pathological angiogenesis.<\/p>                    <\/div>\n\t\t        \n                    <div id=\"selected-publications-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"selected-publications-tab\">\n\t\t\t\t        <p>Magliacane Trotta S., Adinolfi A., D\u2019Orsi L., Panico S., Mercadante G., Mehlen P., Ambati J., De Falco S., <strong>Tarallo V<\/strong>. \u201cCancer-derived exosomal Alu RNA promotes colorectal cancer progression\u201d. Exp Mol Med 56, 700\u2013710 (2024).<\/p><p>PlGF and VEGF-A\/PlGF Heterodimer are Crucial for Recruitment and Activation of Immune Cells During Choroid Neovascularization. <strong>Tarallo V<\/strong>*, Magliacane Trotta S, Panico S, D&#8217;Orsi L, Mercadante G, Cicatiello V, De Falco S. Invest Ophthalmol Vis Sci. 2024 Jul 1;65(8):12. doi: 10.1167\/iovs.65.8.12. *corresponding author<\/p><p>Santonocito M, Zappulla C, Viola S, La Rosa LR, Solfato E, Abbate I, <strong>Tarallo V<\/strong>, Apicella I, Platania CBM, Maugeri G, D&#8217;Agata V, Bucolo C, De Falco S, Mazzone MG, Giuliano F. Assessment of a New Nanostructured Microemulsion System for Ocular Delivery of Sorafenib to Posterior Segment of the Eye. Int J Mol Sci. 2021 Apr 22;22(9):4404. doi: 10.3390\/ijms22094404.<\/p><p>Pignata P, Apicella I, Cicatiello V, Puglisi C, Magliacane Trotta S, Sanges R, <strong>Tarallo V<\/strong>, De Falco S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33918807\/\"><em>Prolyl 3-Hydroxylase 2 Is a Molecular Player of Angiogenesis.<\/em> <\/a>Int J Mol Sci. 2021 Apr 9;22(8):3896. doi: 10.3390\/ijms22083896. *co-last author<\/p><p><strong>Tarallo V<\/strong>, Iaccarino E, Cicatiello V, Sanna R, Ruvo M and De Falco S. <em>Oral delivery of a tetrameric tripeptide inhibitor of VEGFR1 suppresses pathological choroid neovascularization.<\/em> Int J Mol Sci. 2020 Jan 9;21(2):410. doi: 10.3390\/ijms21020410.<\/p><p>Apicella I, Cicatiello V, Acampora D, <strong>Tarallo V<\/strong>*, De Falco S. <em>Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A.<\/em> Cell Rep. 2018 Jun 19;23(12):3635-3646. *co-corresponding author<\/p><p>Di Ruocco F, Basso V, Rivoire M, Mehlen P, Ambati J, De Falco S, <strong>Tarallo V*<\/strong> <em>Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression. <\/em>Oncogene. 2018 Feb 1;37(5):627-637.<\/p><p><strong>Tarallo V,<\/strong> Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, Ponicsan SL, Chaudhuri G, Murphy MP, Dunaief JL, Ambati BK, Ogura Y, Yoo JW, Lee DK, Provost P, Hinton DR, N\u00fa\u00f1ez G, Baffi JZ, Kleinman ME and Ambati J. <em>DICER1 loss and Alu RNA induce age-related macular degeneration via NLRP3 inflammasome and MyD88<\/em>. <strong>Cell.<\/strong> 2012 May 11;149(4):847-59.<\/p><p>Complete List of Published Work in MyBibliography: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/valeria.tarallo.1\/bibliography\/public\/\">https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/valeria.tarallo.1\/bibliography\/public\/<\/a><\/p>                    <\/div>\n\t\t        \n                    <div id=\"professional-experience-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"professional-experience-tab\">\n\t\t\t\t        <p>January 2023 \u2013 present: Senior Researcher at IGB-ABT, CNR Naples<\/p><p>October 2012- present: Researcher at IGB-ABT, CNR, Naples.<\/p><p>January 2010- August 2012: Postdoctoral fellow in the laboratory of Prof. J. Ambati, Department of Ophthalmology and Visual Science, University of Kentucky, Lexington, KY, USA. Topic:\u00a0<em>Study on the mechanisms involved in the Age-related Macular Degeneration (AMD).<\/em><\/p><p>2009: Postdoctoral fellowship, Angiogenesis Lab directed by Dr. Sandro De Falco, IGB-ABT, CNR, Naples, Italy. Topic:\u00a0<em>New inhibitors of VEGF-dependent angiogenesis associated with ocular neovascular diseases<\/em>.<\/p><p>2004-2009:\u00a0Pre-postdoctoral fellow, Angiogenesis Lab directed by Dr. Sandro De Falco, IGB-ABT, CNR, Naples, Italy. Topic:\u00a0<em>Placental Growth Factor variants for inhibition of VEGF-dependent angiogenesis<\/em>.<\/p><p>2002-2004: Undergraduate fellow in the laboratory of Dr. Pasquale Verde, IGB-ABT, CNR, Naples, Italy. Topic:\u00a0<em>Study of the members of AP-1 transcription factor in cancer.<\/em><\/p>                    <\/div>\n\t\t        \n                    <div id=\"research-group-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"research-group-tab\">\n\t\t\t\t        <p><div class=\"tmm tmm_associated-people-tarallo\"><div class=\"tmm_2_columns tmm_wrap tmm_plugin_f\"><span class=\"tmm_two_containers_tablet\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.igb.cnr.it\/index.php\/sara-magliacane-trotta\/\" title=\"Sara Magliacane Trotta\"><div class=\"tmm_photo tmm_pic_associated-people-tarallo_0\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2022\/01\/DSC_0135.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><\/a><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Sara<\/span> <span class=\"tmm_lname\">Magliacane Trotta<\/span><\/div><div class=\"tmm_job\">Researcher<\/div><div class=\"tmm_desc\" style=\"text-align:\"><div class=\"dmb_field dmb_description_of_member\"><p><strong><img decoding=\"async\" class=\"alignnone wp-image-2318\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png\" alt=\"\" width=\"17\" height=\"17\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/Telefono-icona-510x510.png 510w\" sizes=\"(max-width: 17px) 100vw, 17px\" \/><\/strong>\u00a0+39 081 6132601\u00a0\u00a0<img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/>\u00a0 sara.magliacanetrotta@igb.cnr.it<\/p><p><strong>Project Title: <\/strong><em>Alu RNA as a potential regulator of human gastrointestinal cancer progression and metastatic dissemination<\/em><\/p><\/div><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#006293 solid 5px;\"><div class=\"tmm_photo tmm_pic_associated-people-tarallo_1\" style=\"background: url(https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/11\/member-1-1-1-1-1.svg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Antonio<\/span> <span class=\"tmm_lname\">Adinolfi<\/span><\/div><div class=\"tmm_job\">Research fellow<\/div><div class=\"tmm_desc\" style=\"text-align:\"><div class=\"dmb_field dmb_description_of_member\"><div class=\"dmb_field dmb_description_of_member\"><p>\u00a0 <strong><img decoding=\"async\" class=\"alignnone wp-image-2317\" src=\"http:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png\" alt=\"\" width=\"19\" height=\"19\" srcset=\"https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona.png 512w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-300x300.png 300w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-150x150.png 150w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-270x250.png 270w, https:\/\/www.igb.cnr.it\/wp-content\/uploads\/2021\/02\/email-icona-510x510.png 510w\" sizes=\"(max-width: 19px) 100vw, 19px\" \/><\/strong> antonio.adinolfi@igb.cnr.it<\/p><p><strong>Project Title:<\/strong> <em>Studio della fibrosi subretinica conseguente alla maculopatia degenerativa senile<\/em><\/p><\/div><\/div><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div style=\"clear:both;\"><\/div><\/div><\/div><\/div><\/p>                    <\/div>\n\t\t                    <\/div>\n        <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Valeria Tarallo Senior Researcher +39 081 6132 453 \u00a0\u00a0 valeria.tarallo@igb.cnr.it Molecular Oncology Keywords: Alu RNAs, cancer, angiogenesis, AMD Github Twitter Orcid Research Interest Selected Publications Professional Experience Research Group The main research interests are the study of Alu RNAs in cancer progression and in the dry form of age-related macular degeneration and other pathological disorders [&hellip;]<\/p>\n","protected":false},"author":30,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-2515","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2515","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=2515"}],"version-history":[{"count":52,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2515\/revisions"}],"predecessor-version":[{"id":19007,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/2515\/revisions\/19007"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=2515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}