{"id":4275,"date":"2021-07-27T14:16:56","date_gmt":"2021-07-27T12:16:56","guid":{"rendered":"https:\/\/www.igb.cnr.it\/?page_id=4275"},"modified":"2022-01-24T12:37:56","modified_gmt":"2022-01-24T11:37:56","slug":"genetics-genomics-and-epigenetics-of-diseases","status":"publish","type":"page","link":"https:\/\/www.igb.cnr.it\/index.php\/genetics-genomics-and-epigenetics-of-diseases\/","title":{"rendered":"Genetics, Genomics and Epigenetics of Diseases"},"content":{"rendered":"\t\t
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Genetics, Genomics and Epigenetics of Diseases<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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This research area aims at discovering the genetic and epigenetic basis of rare and common diseases as well as the relationship between genes and environment through next-generation genome-wide methodologies and functional studies in a variety of model systems. Research lines are focused on: i) identification and functional characterization of genetic variants under natural selection, in healthy and pathological conditions; ii) molecular mechanisms of human diseases, such as diabetes and thyroid cancer; iii) modulation of pathogenic immune response \u00a0by \u00a0HLA class II genes and other biomarkers \u00a0in coeliac disease; iv) studying the components of the epigenetic machinery (chromatin diseases; CD), the alterations of genetic imprinting and the role of non coding RNAs to understand the interactions between genetics and epigenetics in development and pathophysiology; v) studying rare genetic diseases affecting bone remodeling, nervous system and skin development, or causing kidney failure, heart block disease, cardiomyopathy, myopathy or multi-systemic disorders.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Genetics, Genomics and Epigenetics of Diseases<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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<\/span>
<\/div><\/a>
Marianna<\/span> Aprile<\/span><\/div>
Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Simona<\/span> Cataldi<\/span><\/div>
Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Alfredo<\/span> Ciccodicola<\/span><\/div>
Acting Director<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Valerio<\/span> Costa<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span><\/div><\/span>
<\/div><\/a>
Giovanna<\/span> Del Pozzo<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Floriana<\/span> Della Ragione<\/span><\/div>
Senior Research Technologist<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Teresa<\/span> Esposito<\/span><\/div>
Research Director<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Salvatore<\/span> Fioriniello<\/span><\/div>
Research Technologist<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span><\/div><\/span>
<\/div><\/a>
Francesca<\/span> Fusco<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Fernando<\/span> Gianfrancesco<\/span><\/div>
Research Director<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Giuseppina<\/span> Lacerra<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Maria<\/span> Matarazzo<\/span><\/div>
Research Director<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span><\/div><\/span>
<\/div><\/a>
Maria Giuseppina<\/span> Miano<\/span><\/div>
Senior Researcher<\/div>
\"mariag.miano@igb.cnr.it\"<\/a>\"+390816132261\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Alessandra<\/span> Pescatore<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Laura<\/span> Pisapia<\/span><\/div>
Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Andrea<\/span> Riccio<\/span><\/div>
Honorary Appointment <\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span><\/div><\/span>
<\/div><\/a>
Federica<\/span> Scotto di Carlo<\/span><\/div>
Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Maria<\/span> Strazzullo<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Marcella<\/span> Vacca<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Matilde Valeria<\/span> Ursini<\/span><\/div>
Honorary Appointment <\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
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Population Genetics and Genetic Epidemiology<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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<\/span>
<\/div><\/a>
Marina<\/span> Ciullo<\/span><\/div>
Research Director<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/a>
Teresa<\/span> Nutile<\/span><\/div>
Senior Technologist<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div><\/span>
<\/div><\/a>
Daniela<\/span> Ruggiero<\/span><\/div>
Senior Researcher<\/div>
\"\"<\/a>\"\"<\/a><\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Genetics, Genomics and Epigenetics of Diseases This research area aims at discovering the genetic and epigenetic basis of rare and common diseases as well as the relationship between genes and environment through next-generation genome-wide methodologies and functional studies in a variety of model systems. Research lines are focused on: i) identification and functional characterization of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"class_list":["post-4275","page","type-page","status-publish","czr-hentry"],"_links":{"self":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/4275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/comments?post=4275"}],"version-history":[{"count":46,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/4275\/revisions"}],"predecessor-version":[{"id":12321,"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/pages\/4275\/revisions\/12321"}],"wp:attachment":[{"href":"https:\/\/www.igb.cnr.it\/index.php\/wp-json\/wp\/v2\/media?parent=4275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}