Genetic Park of Cilento and Vallo di Diano


Parco Genetico del Cilento e Vallo di Diano

Publications

  • O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Köttgen A, Stoudmann C, Teumer A, Kutalik Z, Mangino M, Dehghan A, Zhang W, Eiriksdottir G, Li G, Tanaka T, Portas L,et al.
    Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
    PLoS Genet. 2013;9(9):e1003796. doi: 10.1371/journal.pgen.1003796. Epub 2013 Sep 19.PMID: 24068962
     
  • Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, et al.
    Common variants in Mendelian kidney disease genes and their association with renal function.
    J Am Soc Nephrol. 2013 Dec;24(12):2105-17. doi: 10.1681/ASN.2012100983. Epub 2013 Sep 12.PMID: 24029420
     
  • Paul DS, Albers CA, Rendon A, Voss K, Stephens J; HaemGen Consortium, van der Harst P, Chambers JC, Soranzo N, Ouwehand WH, Deloukas P.
    Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.
    Genome Res. 2013 Jul;23(7):1130-41. doi: 10.1101/gr.155127.113. Epub 2013 Apr 9.PMID: 23570689
     
  • Biino G, Santimone I, Minelli C, Sorice R, Frongia B, Traglia M, Ulivi S, Di Castelnuovo A, Gögele M, Nutile T, Francavilla M, Sala C, Pirastu N, Cerletti C, Iacoviello L, Gasparini P, Toniolo D, Ciullo M, Pramstaller P, Pirastu M, de Gaetano G, Balduini CL.
    Age- and sex-related variations in platelet count in Italy: a proposal of reference ranges based on 40987 subjects' data.
    PLoS One. 2013;8(1):e54289. doi: 10.1371/journal.pone.0054289. Epub 2013 Jan 31.PMID: 23382888
     
  • Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J,et al.
    Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
    Nat Genet. 2013 Feb;45(2):145-54. doi: 10.1038/ng.2500. Epub 2012 Dec 23.PMID: 23263486
     
  • van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, et al.
    Seventy-five genetic loci influencing the human red blood cell.
    Nature. 2012 Dec 20;492(7429):369-75. doi: 10.1038/nature11677. Epub 2012 Dec 5.PMID: 23222517
     
  • Nürnberg ST, Rendon A, Smethurst PA, Paul DS, Voss K, Thon JN, Lloyd-Jones H, Sambrook JG, Tijssen MR; HaemGen Consortium, Italiano JE Jr, Deloukas P, Gottgens B, Soranzo N, Ouwehand WH.
    A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.
    Blood. 2012 Dec 6;120(24):4859-68. doi: 10.1182/blood-2012-01-401893. Epub 2012 Sep 12.PMID: 22972982
     
  • Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, et al.
    Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
    Hum Mol Genet. 2012 Dec 15;21(24):5329-43. doi: 10.1093/hmg/dds369. Epub 2012 Sep 8.PMID: 22962313 
     
  • Sorice R, Ruggiero D, Nutile T, Aversano M, Husemoen L, Linneberg A, Bourgain C, Leutenegger AL, Ciullo M.
    Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations.
    PLoS One. 2012;7(8):e42537. doi: 10.1371/journal.pone.0042537. Epub 2012 Aug 20.PMID: 22916133 
     
  • Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, et al.
    Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
    Nat Genet. 2012 Jul 15;44(8):904-9. doi: 10.1038/ng.2352. PMID: 22797727 
     
  • Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, et al.
    Genome-wide association and functional follow-up reveals new  loci for kidney function.
    PLoS Genet. 2012;8(3):e1002584. doi: 10.1371/journal.pgen.1002584. Epub 2012 Mar 29. PMID: 22479191 
     
  • Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, et al. 
    Longevity candidate genes and their association with personality traits in the elderly.
    Am J Med Genet B Neuropsychiatr Genet. 2012 Mar;159B(2):192-200. doi: 10.1002/ajmg.b.32013. Epub 2011 Dec 27. PMID: 22213687
     
  • Biino G, Gasparini P, D'Adamo P, Ciullo M, Nutile T, Toniolo D, Sala C, Minelli C, Gögele M, Balduini CL. 
    Influence of age, sex and ethnicity on platelet count in five Italian geographic isolates: mild thrombocytopenia may be physiological.
    J Haematol. 2011 Dec 15. doi: 10.1111/j.1365-2141.2011.08981.x. PMID: 22171955
     
  • Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, et al.
    New gene functions in megakaryopoiesis and platelet formation. 
    Nature. 2011 Nov 30;480(7376):201-8. doi: 10.1038/nature10659. PMID: 22139419
     
  • Siervo M, Ruggiero D, Sorice R, Nutile T, Aversano M, Iafusco M, Vetrano F, Wells JC, Stephan BC, Ciullo M. 
    Body mass index is directly associated with biomarkers of angiogenesis and inflammation in children and adolescents.
    Nutrition. 2011 Nov 22. PMID: 22113066
     
  • Terracciano A., Esko T., Sutin A.R., de Moor M.H.M., Meirelles O., Zhu G., Tanaka T., Giegling I., Nutile T., Realo A., Allik J., Hansell N.K., Wright M.J., Montgomery G.W., Willemsen G., Hottenga J-J, Friedl M., Ruggiero D., Sorice R., Sanna S., Cannas A., Räikkönen K., Widen E., Palotie A., Eriksson J.G., Cucca F., Krueger, R.F. Lahti J., Luciano M., Smoller J.W., van Duijn C.M., Abecasis G.R., Boomsma D.I., Ciullo M., et al.
    Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with Excitement-Seeking.
    Translational Psychiatric 2011, 1, e49; doi:10.1038/tp.2011.42 Published online 18 October 2011
     
  • Girotto G, Pirastu N, Sorice R, Biino G, Campbell H, d'Adamo AP, Hastie ND, Nutile T, Polasek O, Portas L, Rudan I, Ulivi S, Zemunik T, Wright AF, Ciullo M, Hayward C, Pirastu M, Gasparini P.
    Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways. 
    J Med Genet. 2011 Jun;48(6):369-74. doi: 10.1136/jmg.2010.088310. Epub 2011 Apr 14. PMID: 21493956
     
  • Daniela Ruggiero, Cyril Dalmasso, Teresa Nutile, Rossella Sorice, Laura Dionisi, Mario Aversano, Philippe Bröet, Anne-Louise Leutenegger, Catherine Bourgain, Marina Ciullo 
    Genetics of VEGF Serum Variation in Human Isolated Populations of Cilento: Importance of VEGF Polymorphisms
    PLoS ONE 2011 6(2): e16982.
     
  • Sorice R, Bione S, Sansanelli S, Ulivi S, Athanasakis E, Lanzara C, Nutile T, Sala C, Camaschella C, D'Adamo P, Gasparini P, Ciullo M, Toniolo D.
    Association of a variant in the CHRNA5-A3-B4 gene cluster region to heavy smoking in the Italian population.
    Eur J Hum Genet. 2011 Jan 19.
     
  • de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza R, Nutile T, Ciullo M, Rujescu D, Giegling I, Konte B, Widen E, Cousminer DL, Eriksson JG, Palotie A, Peltonen L, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Räikkönen K, Bierut LJ, Martin NG, van Duijn CM, Boomsma DI.
    Meta-analysis of genome-wide association studies for personality.
    Mol Psychiatry. 2010 Dec 21. 
     
  • Siervo M, Ruggiero D, Sorice R, Nutile T, Aversano M, Stephan BC, Ciullo M.
    Angiogenesis and biomarkers of cardiovascular risk in adults with metabolic syndrome.
    J Intern Med. 2010 Oct;268(4):338-47.
     
  • Colonna V, Nutile T,Ferrucci RR, Fardella G, Aversano M, Barbujani G, Ciullo M
    Comparing population structure as inferred from genealogical versus genetic information
    European Journal of Human Genetics 24 June 2009
     
  • Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE.
    Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
    PLoS Genet. 2009 Oct;5(10) PMID: 19851442
     
  • Bedin E, Franzè A, Zadro C, Persico MG, Ciullo M, Hladnik U, Dolcetta D, Grasso DL, Riccardi P, Nutile T, Andrighetto G, D'Adamo P, Gasparini P, Marciano E.
    Age-related hearing loss in four Italian genetic isolates: an epidemiological study.
    Int J Audiol. 2009;48(7):465-72. PMID: 19925333
     
  • Traglia M, Sala C, Masciullo C, Cverhova V, Lori F, Pistis G, Bione S, Gasparini P, Ulivi S, Ciullo M, Nutile T, Bosi E, Sirtori M, Mignogna G, Rubinacci A, Buetti I, Camaschella C, Petretto E, Toniolo D.
    Heritability and demographic analyses in the large isolated population of val borbera suggest advantages in mapping complex traits genes.
    PLoS One. 2009 Oct 22;4(10)PMID: 19847309
     
  • Ciullo M, Nutile T, Dalmasso C, Sorice R, Bellenguez C, Colonna V, Persico MG, Bourgain C
    Identification and replication of a novel obesity locus on chromosome 1q24 in isolated populations of Cilento.
    Diabetes 2008 Mar;57(3):783-90. Epub 2007 Dec 27.
     
  • Sala C, Ciullo M, Lanzara C, Nutile T, Bione S, Massacane R, d'Adamo P, Gasparini P, Toniolo D, Camaschella C
    Variation of hemoglobin levels in normal Italian populations from genetic isolates.
    Haematologica  2008 Sep;93(9):1372-5. Epub 2008 Jul 4.
     
  • Colonna V, Nutile T, Astore M, Guardiola O, Antoniol G, Ciullo M, Persico MG.
    Campora: a young genetic isolate in South Italy.
    Human Heredity 2007;64(2):123-35. Epub 2007 May 2.
     
  • Ciullo M, Bellenguez C, Colonna V, Nutile T, Calabria A, Pacente R, Iovino G, Trimarco B, Bourgain C, Persico MG.
    New susceptibility locus for hypertension on chromosome 8q by efficient pedigree-breaking in an Italian isolate.
    Human molecular genetics 2006 May 15;15(10):1735-43. Epub 2006 Apr 12.