Professor of Epigenetics

KAUST Environmental Epigenetics Research Program

Biological and Environmental Sciences and Engineering Division

4700 King Abdullah University of Science and Technology

Thuwal 23955-6900, Saudi Arabia

Email:Valerio.orlando@kaust.edu.sa

https: keep.kaust.edu.sa

IGB Seminar 22 Maggio 2023 - OrlandoProf. Valerio Orlando obtained his PhD in Molecular Biology at University La Sapienza in Rome Italy, then he went on for postdoc in Epigenetics in Renato Paro’s lab, at ZMBH Heidelberg (1991- 1997) where he pioneered the worldwide used Chromatin Immunoprecipitation (ChIP) technology (Orlando and Paro, Cell 1993; Orlando et al EMBO J 1998, Orlando TIG 2000). In his subsequent work he carried on the work on the mechanistic role of Polycomb proteins cell memory system in the context of nuclear architecture, noncoding RNA and basal transcription regulation (Breiling et al, Nature 2001, Breiling et al, Mol Cell 2001, Orlando V Cell 2003, Lanzuolo et al Nat Cell Biol, 2007, Cernilogar et al Nature 2011).

He started his independent career in 1998 at San Raffaele Institute in Milan where he established the Laboratory of Epigenetics and Genome reprogramming. In 2002 he joined Telethon Foundation and he moved to IGB CNR New Campus in Naples (2002-2008) where he was founder member of the Dulbecco Telethon Institute (DTI), and later to Rome at Santa Lucia Foundation Hospital and Research Center (2008-2013). He has been a proactive member of Eu-funded Network of Excellence of Epigenetics (Epigenome and Epigenesys Networks of Excellence) and spearheader of the First National Italy’s Flagship Project on Epigenetics (www.epigen.it). In 2013 He moved to KAUST where he founded the KAUST Environmental Epigenetics program (KEEP; keep.kaust.edu.sa).