Welcome to IGB-CNR

The Institute of Genetics and Biophysics Adriano Buzzati-Traverso (IGB-ABT) is part of the Department of Biomedical Sciences (DSB) of the National Research Council (CNR). The IGB-ABT is a worldwide recognized institution devoted to basic and applied research. The research activity aims at the comprehension of fundamental genetic and epigenetic mechanisms controlling mammalian cell state and cell identity from  embryonic development to post-natal life, both in normal and pathological conditions, through a multidisciplinary, convergent and integrated approach. This approach is applied to different research fields: stem cell biology, embryonic development and organogenesis, neurobiology, human genetics, molecular oncology, angiogenesis and immunology.

Research Areas

The research carried out at the IGB aims to understand the molecular basis controlling genetically and epigenetically the cell state and cell identity during embryonic development and post-natal life, in normal and pathological conditions. These activities are organized in two main areas:

Developmental Biology and Genetics

Molecular Mechanisms of Human Diseases

2025 January

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🚀 Our latest publication explores a novel hybrid nanosystem for #CRC that uses gold nanoparticles and anti-L1CAM antibodies to deliver the TGF-β inhibitor galunisertib directly to tumor-initiating cells. @AIRC_it @CnrIgb @CNRsocial_ @DonatellaCave

Next IGB seminar will be held next Monday by Dr Daniele Fachinetti from Institut Curie (Paris, France), at 12 pm in the CNR Conference Room. Join us to uncover novel issues in the fields of DNA replication, cell division, and genome integrity!

The @CnrIgb/@EMBO meeting just started in the sunlight shining island of Capri. Thanks to EMBO and all organizers, @EnzaLonardo1, @MariaPiaShiva, Valerio Costa, @ArlottaLab, @ParmarLab, @AnnalisaFico, @Fiorenzano555, for bringing back to Capri our 30th institutional workshop

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