- Research Interest
- Selected Publications
- Professional Experience
- Research Group
- Patent of a new assay for celiac disease diagnosis: A.T.CD4, gliadin activated CD4+ T cells (Rif. CNR 11009 – ID n .2426).
- Study of HLA class II genes expression in antigen presenting cells from patients affected by autoimmunity.
- Analysis of the immune response of gliadin-specific CD4+ T lymphocytes in patients with active celiac disease and patients in remission after gluten-free diet.
- Analysis of immunomodulatory role of exosomes from Mesenchymal Stem Cells
- Monitoring of antigen-specific CD4+ and CD8+ lymphocyte activation, in patients and healthy donors, following Sars-Cov2 vaccine administration, by flow cytometry immunophenotyping.
- S Sartoris, G Del Pozzo. Exploring the HLA complex in autoimmunity: From the risk haplotypes to the modulation of expression. Clinical Immunology Aug.2024. 265, 110266
- M Laezza, L Pisapia, B Toro, V Mercadante, A Rispo, C Gianfrani, Del Pozzo. Changes upon the gluten-free diet of HLA-DQ2 and TRAFD1 gene expression in peripheral blood of celiac disease patients. Journal of Translational Autoimmunity. Jun 2014. 8, 100240
- Del Mastro A…Del Pozzo and C. Gianfrani. Booster Dose of SARS-CoV-2 mRNA Vaccine in Kidney Transplanted Patients Induces Wuhan-Hu-1 Specific Neutralizing Antibodies and T Cell Activation but Lower Response against Omicron Variant. Viruses May 2023, 15, 1132.
- Farina F., Pisapia L., Laezza, MV, Serena G, Rispo A., Ricciolino S, Gianfrani C, Fasano Alessio , Del Pozzo G. Effect of Gliadin Stimulation on HLA-DQ2.5 Gene Expression in Macrophages from Adult Celiac Disease Patients. Biomedicines 2021 Dec 29;10(1):63.
- Del Pozzo G., Farina F., Picascia S., Laezza M., Vitale S., Gianfrani C., HLA class II genes in precision-based care of childhood diseases: what we can learn from celiac disease. Pediatric Research 2021, 89, 307–312.
- Pisapia L., Picascia S., Farina F., Barba P., Gianfrani C., Del Pozzo G., Differential expression of predisposing HLA-DQ2.5 alleles in DR5/DR7 celiac disease patients affects the pathological immune response to gluten. Scientific Reports 2020, Oct 14;10(1):17227.
- Pisapia L., Hamilton R.S., Farina F., D’Agostino V., Barba P.; Strazzullo M., Provenzani A., Gianfrani C., Del Pozzo G., Tristetraprolin/ZFP36 Regulates the Turnover of Autoimmune-Associated HLA-DQ mRNAs. Cells 2019, 8.
- Farina F., Picascia S., Pisapia L., Barba P., Vitale S., Franzese A., Mozzillo E., Gianfrani C., Del Pozzo G., HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, are More Expressed Than Non-Predisposing Alleles and are Coordinately Regulated. Cells 2019, 8, 751.
- Pisapia L., Cerillo I., Farina F., Zimbardo A., Barba P., Orefice G., Gianfrani C., Strazzullo M., Del Pozzo G., The HLA-DRB1 risk alleles for multiple sclerosis are differentially expressed in blood cells of patients from Southern Italy. International Journal of Immunogenetics 2019, 46, 479–484
- Gianfrani C., Pisapia L., Picascia S., Strazzullo M., Del Pozzo G., Expression level of risk genes of MHC class II is a susceptibility factor for autoimmunity: New insights. Journal of Autoimmunity 2018, 89, 1–10.
- Pisapia L., Camarca A., Picascia S., Bassi V., Barba P., Del Pozzo G., Gianfrani C., HLA-DQ2.5 genes associated with celiac disease risk are preferentially expressed with respect to non-predisposing HLA genes: Implication for anti-gluten T cell response. Journal of Autoimmunity 2016, 70, 63–72.
- 1994-2007 CNR Researcher Scientist
- 2004-present Immunobiology Group leader at Institute of Genetics and Biophysics, CNR, Naples
- 2007–present CNR Senior Researcher Scientist
- Reviewer for ISI scientific journals in the field of immunology and molecular biology
- Supervisor of Master Degree and PhD theses at Federico II University and Luigi Vanvitelli University in Naples